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November 1960

Infectious Diseases: Twenty-Fifth Annual Review of Significant Publications

Author Affiliations

Philadelphia, Pa.

Arch Intern Med. 1960;106(5):679-713. doi:10.1001/archinte.1960.03820050091015

Seven Nobel prizes awarded for advances in knowledge in the field of infectious diseases indicate how great progress has been in the past quarter century. So honored were the discoverers of sulfonamides, penicillin, streptomycin, and chlorophenothane (D.D.T.); of the means to cultivate viruses easily; of a new biologic concept of viruses, and of a mode of microbic genetics. To these advances may be added the coming-of-age of virology with the introduction of diagnostic methods to discover and sort out many previously ignored or undefined infections, and the development of specific vaccines. The detection and identification of inapparent and mild infections broadened the epidemiologic spectrum of many diseases. This improvement together with the substitution of etiologic diagnoses for anatomic or symptomatic diagnoses permitted an approach toward statistical accuracy in estimating the actual incidence and mortality rate of many diseases. Logical measures of prevention and treatment also ensued. Dif- ferent viruses were

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