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November 1960

Dermatologic Medications.

Arch Intern Med. 1960;106(5):737-738. doi:10.1001/archinte.1960.03820050149020

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This is a delightful and valuable little book. It offers the physician quick chemical insight into a field otherwise somewhat obscured by names and counternames, as well as claims and counterclaims. By means of two hundred and fifty structural formulae, all uniquely drawn to point up the similarities of drugs which namewise appear totally dissimilar, the Lerner volume stimulates a thoughtful assessment of any therapeutic approach.

It is the kind of a book that needs no reviews since its sinews are clearly in view. Yet for those who are denied the joys of bookstore browsing, let us cite just one example of the Lerner approach. The section on antihistaminic drugs describes twenty-four currently prescribable compounds. We are given a chance to see "molecularly" how the -CH2 CH2N- side-chain is common to histamine and the antihistaminics. We are also shown how the most modern antihistaminic is virtually a

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