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The knowledge of medicine advances when a disease entity or syndrome is identified and described, when clinical research brings the aid of the laboratory to the bedside in the illumination and elucidation of the secret processes of disease, when the natural history of disease in an individual patient is scrutinized and delineated, or when the broad pattern of a disease as it affects large numbers of people is evolved from a properly designed field investigation. Dr. L. J. Witts, Nuffield Professor of Clinical Medicine at Oxford, has called on a number of his distinguished British colleagues to describe many of the aspects of clinical science which relate to such problems. The chapters are brief, concise, but give a surprisingly comprehensive picture of the major methods of clinical trials and field studies. Emphasis on a sound knowledge of statistical theory and practice, a discussion of the methodology of collecting and analyzing
Bean WB. Medical Surveys and Clinical Trials. Arch Intern Med. 1961;107(2):311. doi:10.1001/archinte.1961.03620020161022
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