During the last decade considerable advances have been made in the field of communicable disease control. Concomitantly many new immunizing agents and procedures have been developed and have amply demonstrated their effectiveness. The past years have also seen a continuing effort to improve old procedures and agents and to apply this information to the prevention of disease. Such new and significant changes necessitate periodic evaluation. This paper is an attempt to review immunization procedures in general and to relate recent developments to our changing vaccination programs.
There are few diseases which have exerted so profound an effect on the history of mankind as that of smallpox which, because of its high mortality and disfiguring effects, still continues to be one of the most feared of all contagious diseases. The protective efficacy of smallpox vaccination has been conclusively demonstrated, and this procedure remains as one of the outstanding public
MENZIN AW. Current Immunization Methods and Materials: A Review. Arch Intern Med. 1961;107(3):409–429. doi:10.1001/archinte.1961.03620030097015
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