Of the various diverticula arising in the gastrointestinal tract, those occurring in the jejunum have seldom stimulated great clinical interest. Typically asymptomatic, jejunal diverticula give rise only rarely to nonspecific complications such as perforation and hemorrhage. However, as is now established, jejunal diverticula have the unique potentiality of simulating certain clinical syndromes. The association of such diverticula with megaloblastic anemia and malabsorption has enlarged the differential diagnosis and the clinical management of these conditions.Since 1949, twenty-five cases of jejunal diverticulosis, megaloblastic anemia, and/or intestinal malabsorption have been reported,* reflecting both the infrequency and the increasing recognition of the syndrome.4-21 Jejunal diverticulosis, invariably present, has frequently been associated with other intestinal diverticula. Of these cases the predominant finding was anemia or defective absorption of Vitamin B12 in 9, steatorrhea in 3, and combinations of these abnormalities in the remainder. The bone marrow was megaloblastic in 16 of
JOHNSON PM, WYSOR WG, HILL C. Mimetic Aspects of Small Intestinal Diverticulosis: A Report of Four Cases. Arch Intern Med. 1961;108(3):370–375. doi:10.1001/archinte.1961.03620090042005
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.