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October 1961


Author Affiliations

251 E. Chicago Ave. Chicago 11, Ill.

Arch Intern Med. 1961;108(4):614. doi:10.1001/archinte.1961.03620100106016

Dr. Maxwell Finland has called my attention to my editorial in the June, 1961, issue of the Archives of Internal Medicine1 in which it is stated on p. 811 that Roberts, Perry, Kuharic, and Kirby2 came to different conclusions regarding the therapeutic efficacy of demethylchlortetracycline than those arrived at by Hirsch and Finland,3 possibly because a different test micro-organism was used by the two groups—namely, a Group A Streptococcus by Roberts et al. and Bacillus cereus by Hirsch and Finland. Roberts and his associates, who had not used B. cereus but had used a streptococcal strain, pointed out this difference. They did not point out that Finland and his associates3,4 had, in addition, used a Group A streptococcus and a staphylococcus strain as well and that their results also showed a more prolonged antibacterial effect in the serum of persons receiving doses of demethylchlortetracycline against the

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