Almost every organ in the body has been known to contain the typical lesions of lymphosarcoma. Primary lymphosarcoma of the prostate gland is rare, and only about 22 cases have been reported in the medical literature. These were reviewed in an excellent article by Waller and Shullenberger1 in 1949. They stated that the first authentic case was reported by Coupland in 1877. It appears that some of the reported cases lacked biopsy proof and other substantial evidence that the disease was primary in the prostate gland.2 No case has been reported for the past 10 years.In a review of 196 cases of lymphosarcoma, Sugarbaker and associates3 noted primary extranodal foci in about 1% of cases. They stated that secondary prostatic involvement apparently did not occur.The records at the Lexington Clinic were reviewed covering the years 1926-1960. No cases of prostatic infiltration with lymphosarcoma were
WEST WO. Primary Lymphosarcoma of Prostate Gland. Arch Intern Med. 1962;109(4):469–472. doi:10.1001/archinte.1962.03620160095013
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