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July 1962

Reduction of Hypertension After Liver Disease

Author Affiliations


Research Department, St. Vincent Charity Hospital, Cleveland.

Arch Intern Med. 1962;110(1):45-49. doi:10.1001/archinte.1962.03620190047006

Prolonged remission of well-established hypertension is infrequently observed. In 1924 O'Hare1 was the first to describe normal blood pressures in patients demonstrating retinopathy attributable to previously documented hypertension. Meakins2 in 1932 noted return of blood pressure from hypertensive to normal levels with the onset of jaundice. Schwab3 has described cases of hypertensive cardiovascular disease with congestive heart failure and liver engorgement which had become and remained normotensive. Studying human necropsy material, Raaschou4 concluded that severe impairment of liver function by chronic hepatitis may produce normalization of the blood pressure in hypertension.

Hypertension and milder forms of cirrhosis of the liver are not infrequently coincident in the same person, since both are diseases of late and middle life. A review of records of more than 500 patients with hepatic cirrhosis5 revealed 90 with a systolic pressure of 150 or greater, of which only 60 had a

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