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July 1962

Herpes Zoster Generalisatus Pneumonia: Varicella Pneumonia in a Patient with Herpes Zoster Generalisatus; Report of a Case in a Patient with Hodgkin's Disease

Author Affiliations


From the Department of Medicine, Stanford University School of Medicine.; Resident in Medicine (Dr. Kain), Intern in Medicine (Dr. Feldman), and Clinical Clerk in Medicine (Mr. Cohn), Stanford Medical Center, Palo Alto, Calif.

Arch Intern Med. 1962;110(1):98-101. doi:10.1001/archinte.1962.03620190100015

Although but a single virus is thought to be responsible for both varicella and herpes zoster, we have found no case report of viral pneumonitis associated with the latter, even when it has become generalized. We wish here to report such a case occurring in a patient with long-standing Hodgkin's disease.

Report of Case  A 45-year-old white housewife with Hodgkin's disease since 1954 was admitted to the medical service of the Stanford Medical Center on Oct. 20, 1960, because of acute dyspnea, high fever, and cough.Asymptomatic except for generalized pruritus, 11 days prior to admission the patient developed a painful eruption involving the right posterior inframandibular area and a low-grade fever. A clinical diagnosis of herpes zoster was made. She was treated with Protamide, Pituitrin, thiamine, immune serum globulin, streptokinase-streptodornase, and topical but not systemic adrenal corticosteroids. Vesicles appeared, coalesced, became hemorrhagic and necrotic, and rapidly covered the entire

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