Idiopathic pulmonary hemosiderosis (essential brown induration of the lungs), first described by Virchow1 in 1864, has been reported in 52 adult patients.
After Virchow's description, there was no further report of the disease until Ceelen2 published autopsy findings in 2 children in 1931. The first adult cases were reported by Waldenstrom3 in 1940, who described the clinical and roentgenologic findings in a 16-year-old girl, and Borsos-Nachtnebel4 in 1942, who described the findings in a 38-year-old man. Since Browning and Houghton5 reported 3 adult cases in 1956, there have been 156,15,49,50 additional adult cases described in the American literature.
Despite its characteristic nature, idiopathic pulmonary hemosiderosis is probably still poorly recognized and surely incompletely understood. Because the disorder is rare the following case is described in detail and the literature reviewed.
Report of a Case
A 19-year-old soldier was first hospitalized on Jan. 21, 1960,
OGNIBENE AJ, JOHNSON DE. Idiopathic Pulmonary Hemosiderosis in AdultsReport of Case and Review of Literature. Arch Intern Med. 1963;111(4):503–510. doi:10.1001/archinte.1963.03620280103016
Customize your JAMA Network experience by selecting one or more topics from the list below.