The osseous manifestations of sarcoidosis have played a prominent role in the recognition of the systemic nature of this disease.1 The incidence of osseous involvement in this country has been approximately 20%,2-6 in contrast to the more frequent hilar and pulmonary disease (84%).7 The phalanges, metacarpals, and metatarsals have been the usual sites of these lesions; involvement has not been limited, however, to short tubular bones. Extensive changes in the long tubular bones1,3,8 and, rarely, in the skull and spinal column have been reported.9 There are only 2 cases in the literature with a biopsy-proved antemortem diagnosis of vertebral sarcoidosis.10,11 This paper describes the clinical and roentgenological manifestations of vertebral sarcoidosis, reviews the literature, and presents a patient in whom vertebral involvement produced the initial symptoms of sarcoidosis.
Report of a Case
A 33-year-old Negro female, born in North Carolina, was in good health
ZENER JC, ALPERT M, KLAINER LM. Vertebral Sarcoidosis. Arch Intern Med. 1963;111(6):696–702. doi:10.1001/archinte.1963.03620300016004
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