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June 1963

Acute Hyperparathyroidism: Report of a Fatal Case, with ECG Findings

Author Affiliations


Professor of Medicine (Dr. Naik); Assistant Professor of Medicine (Dr. Sarma); Professor of Pathology (Dr. Gopalrao); Osmania Medical College.

Arch Intern Med. 1963;111(6):729-733. doi:10.1001/archinte.1963.03620300049009

Acute hyperparathyroidism, otherwise known as parathyroid crisis or parathyrotoxicosis, is a rare and unpredictable event in the course of clinical hyperparathyroidism which usually follows a chronic course extending into decades. If untreated the acute condition is invariably fatal, and rapidly so.

Hewson,1 while reporting a fatal case, reviewed in detail 22 cases reported till then. Nelson2 reviewed 24 cases and added three of his own. Including two out of the five reported by Waife,3 three by Thomas et al,4 and one each by Fitz,5 Horowitz,6 and Spinner7 the total comes to not less than 35 so far. At least 11 of these have been saved by operation.

The case presented herewith, besides being typical of the other cases reported, shows several interesting features.

Report of Case  A Hindu male aged about 45 years was admitted on May 27, 1961, in a stuporous condition

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