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June 1963

Eosinophilic Pleural Effusion: A Clue in Differential Diagnosis

Author Affiliations


Arch Intern Med. 1963;111(6):809-813. doi:10.1001/archinte.1963.03620300129020

Pleural effusion in which a high proportion of the cells are eosinophils is not a widely recognized phenomenon. One purpose of this paper is to report that the cause of such an effusion may be a fungus infection. Two patients with eosinophilic effusion are described in detail, and several others of which we have knowledge are mentioned briefly. Finally, we will review the pertinent literature on this subject.

Report of Cases 

Case 1.—  A 42-year-old male laborer was admitted to the Albuquerque Veterans Hospital on Dec. 5, 1961, with acute pleuritic left lateral chest pain of one week's duration. He had come to New Mexico from California about ten days previously, working as an itinerant laborer, and shortly thereafter had become ill as described, with temperature up to 102 F and severe malaise. There was a history of vague aching in the chest, knees, and hips together with slight dyspnea

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