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July 1963

The Dyslipidoses.

Arch Intern Med. 1963;112(1):141. doi:10.1001/archinte.1963.03860010167024

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The Dyslipidoses presents a comprehensive review of the primary and secondary diseases of lipid metabolism. These include disorders characterized by elevated serum lipids, such as xanthomatous familial hypercholesteremia and the nephrotic syndrome as well as those metabolic aberrations such as Gaucher's disease or Niemann-Pick's disease which have normal serum lipids and intracellular deposits of lipids.

Obviously this book will be valuable as a reference for students of atherosclerosis and coronary heart disease as well as for those primarily interested in the clinical aspects of lipid disorders. These vascular entities are, for the most part, disorders of lipid metabolism. That such vascular lipid deposits have genetic causation is illustrated especially well in the family backgrounds of the patients with hypercholesteremic xanthomatosis. Some relatives have the triad of coronary heart disease, xanthoma, and elevated serum cholesterol concentration. Others lack xanthoma and have only hypercholesteremia and coronary disease. Such persons resemble closely the

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