There are two ways of finding out what happens to people who habitually eat food which differs from that eaten by Americans. Neither way is easy. One is to see what happens to volunteers in North America or Western Europe who eat an experimental diet for many years. Studies of this kind in outpatients may be unreliable, and inpatient studies are difficult and expensive. The second way is to study people in poor or materially poor—the two are not synonymous—countries of the world where the native eats a high-carbohydrate, low-fat, low-cholesterol diet because he cannot afford to eat richer food.
Many people whose judgment I respect believe that the epidemiologie evidence obtained by the latter method supports the fact that there is a correlation between elevated serum lipid levels and the incidence of atherosclerosis or the prevalence of illness by atherosclerosis. I am all in favor of trying to establish
Stone DB. Diabetes Mellitus in the Tropics. Arch Intern Med. 1963;112(2):284–285. doi:10.1001/archinte.1963.03860020182026
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