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September 1963

Surgical and Hormonal Therapy of Adult Female Intersex: Rationale in a Case With Erroneous Sex Assignment

Author Affiliations


Departments of Medicine, Welborn Clinic and the Welborn Memorial Baptist Hospital, Evansville, Ind (Dr. Ewer); departments of urology, Welborn Clinic and the Welborn Memorial Baptist Hospital, Evansville, Ind (Dr. Kelly); Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Mich (Dr. Shaw).

Arch Intern Med. 1963;112(3):377-385. doi:10.1001/archinte.1963.03860030131014

Patients with intersex states and inappropriate sex assignment who remain untreated until adult life pose difficult technical, psychological, and medicolegal problems. Because the cases are rare and show great variation in the multiple pathogenic factors involved, decisions regarding treatment are difficult to make in the individual case. The purpose of this communication is to report in detail an adult, female intersex who was reared in opposition to his anatomic and genetic sex, but in whom surgical and hormonal treatment augmented social rehabilitation.* Information about the patient's mother that is pertinent to the etiologic classification of the female intersex state is included.

Report of Case 

First Interview.  —A 31-year-old Negro was referred for study by his family physician because of sexual dimorphism. The patient said that he was born an illegitimate child and that he was raised by his mother and stepfather. He said that he had a penis and until