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September 1963

Scalene Node Sarcoidosis"Benign or Malignant?

Arch Intern Med. 1963;112(3):397-400. doi:10.1001/archinte.1963.03860030151017

Biopsy of the scalene lymph nodes is frequently done inan attempt to diagnose pulmonary disease.1 While this procedure is often rewarding, uncritical acceptance of a diagnosis based on such a biopsy can lead to error. The case reported here, a patient with pulmonary carcinoma in whom the histology of the scalene lymph node was compatible with sarcoid, illustrates this hazard. We would like to emphasize in this report that sarcoid-like lesions occur in scalene lymph nodes in association with lung carcinomas, and the clinician who is unaware of this association may fail to diagnose an underlying malignancy.

Report of Case  A 48-year-old Negro female was admitted to Detroit Receiving Hospital on Jan 11, 1962, with a chief complaint of loss of appetite of five weeks' duration. She had lost 27 pounds in five weeks. She developed shortness of breath and wheezing four weeks prior to admission. She denied cough,

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