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September 1963

The Red Cell, Production, Metabolism, Destruction: Normal and Abnormal.

Arch Intern Med. 1963;112(3):442-443. doi:10.1001/archinte.1963.03860030196031

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A rich advowson, highly prized, For private sale was advertized;

W. S. Gilbert, The Reverend Simon Magus

My seven-year-old daughter's current emphasizer is "Holy Toledo," an expression to which she attaches mystical, quasireligious significance despite parental admonitions to the contrary. I can think of no better expression to state my view of Dr. Harris's text. HOLY TOLEDO, WHAT A BOOK! It is the biography of a cell, its normal role, its vagaries, the pitfalls and stresses it encounters in the society of the human body. Deviations from normal are traced to their presently understood source, and the relation of clinical disease to defects in porphyrin synthesis, the formation of globin, iron lack, and a multitude of other factors are carefully developed. The organization of the text into basic physical and chemical cell structure, defects in this formation, the clinical disease which results, and the therapy dictated by the fundamental disturbance

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