This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
In 1915, Sir William Osler, in his article on arteriosclerosis in the Osler System of Medicine, attributed this disorder chiefly to the "wear and tear of life." "Overuse (of the arteries) leads to degeneration; in time they grow old—the limit of their endurance is reached and they wear out." It is only fair to add that essentially the same view has generally been held until relatively recently. This simple concept is now outdated. The purpose of the present volume is to examine the role of the numerous factors that are now considered to be of possible significance in the etiology of myocardial infarction and of its most important immediate cause, coronary atherosclerosis.
It is rather astonishing that, in a symposium devoted to the question of the etiology of myocardial infarction, there is not a single paper on the role of diet in producing the plasma lipid disturbances that are thought
Resnik WH. The Etiology of Myocardial Infarction.. Arch Intern Med. 1963;112(5):792. doi:10.1001/archinte.1963.03860050179030
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: