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December 1963

Universal Angiomatosis

Author Affiliations


From the Department of Internal Medicine of the College of Medicine of the State University of Iowa.

Arch Intern Med. 1963;112(6):869-874. doi:10.1001/archinte.1963.03860060107011

Some time ago we assumed that medical papers with such titles as "On Telangiectasis Circumscripta Universalis," "Generalized Angiomatosis (Telangiectasia)," "Generalized Telangiectasia (Livedo Racemosa)," and "Generalized Telangiectasia" written by Osler,1 Madden,2 Stokes,3 Ormsby and Mitchell,4 and Becker 5 must have referred to a lesion or lesions which pervaded the entire body of the patient. In Vascular Spiders and Related Lesions of the Skin6 one of us (W.B.B.) called attention to an example of angiomatosis which affected not only blood vessels of all the skin and mucous surfaces available for inspection, but in addition the lining of many of the body's tubular transport systems and the intimate vascular skeleton of every organ into which bleeding can call attention to itself by a recognizable sign or symptom. We have written to a number of dermatologists7 who have not recognized a comparable case and who cannot remember having read about any such disorder. It