A systemic disease may be signalized by telangiectases in the integument.1 These lesions have been observed in such disorders as scleroderma, disseminated lupus erythematosus, Raynaud's disease, telangiectasia ataxia, generalized telangiectasia, and hereditary hemorrhagic telangiectasia. In the latter illness centrifugal and lip spots may help differentiate this disease from others.2
The purpose of this report is to emphasize that skin telangiectases clinically indistinguishable from some of those found in hereditary hemorrhagic telangiectasia occur more frequently than is generally appreciated. Their diagnositic significance is assessed.
A total of 9,416 adult patients and hospital employees at the Boston City Hospital and the University of Utah Affiliated Hospitals and 23 patients with hyperthyroidism at the Pratt Clinic-New England Center Hospital and the Peter Bent Brigham Hospital were examined. Most of the patients were white. The majority of these examinations were conducted during a single short period of time. Individuals demonstrating
BROWN GR. Cutaneous Telangiectases on Lips and Extremities. Arch Intern Med. 1963;112(6):889–891. doi:10.1001/archinte.1963.03860060113012
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