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July 1964

Chronic Meningococcemia: Further Comments on the Pathogenesis of Associated Skin Lesions

Author Affiliations


Chief, Medical Service (Maj Ognibene); Chief, Laboratory Service (Maj Dito).; From the Medical and Laboratory Service of the United States Army Hospital, Nurnberg, Germany.

Arch Intern Med. 1964;114(1):29-32. doi:10.1001/archinte.1964.03860070075005

Since the clinical syndrome of meningococcemia without meningitis was initially described by Salomon,1 numerous reports of chronic meningococcemia have appeared in the American literature.2-10 Benoit's 11 recent report constituted a review of the entire literature to date. It is the purpose of this report to re-emphasize some of the clinical features of the disease and to record distinctive features of the histopathology of the skin lesions. The skin lesion of chronic meningococcemia appears to differ from that of acute meningococcemia. These differences will be reviewed and a possible explanation offered.

Report of a Case  A 26-year-old airman gave a history of good health until July 17, 1962, when he noted the acute onset of fever with chills. On the third day a rash appeared on the feet and hands which was described by the patient as "little red spots." Because of these symptoms he was detained at a