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June 1965

Chondrocalcinosis Coincidental to Other Rheumatic Disease

Author Affiliations


From the departments of medicine and radiology, Western Reserve University School of Medicine. Senior Instructor in Medicine (Dr. Moskowitz) and Assistant Professor of Radiology (Dr. Katz).

Arch Intern Med. 1965;115(6):680-683. doi:10.1001/archinte.1960.03860180052009

Articular chondrocalcinosis ("pseudogout" syndrome) appears to represent a fairly specific disease entity, characterized clinically by acute and chronic arthritis and pathologically by calcium crystals in synovial fluid, cartilage, and periarticular tissue structures.1,2 McCarty suggested the term pseudogout for this syndrome, which at times may resemble acute gouty arthritis, and classified it as possible, probable, or definite depending on clinical, synovial fluid, and x-ray findings.3 Most investigators working in this field would agree, however, that the term pseudogout appears less than ideal in describing the various phases of the clinical spectrum associated with this disease.4,5 The present report is a study of four cases of chondrocalcinosis which appear to represent asymptomatic chondrocalcinosis occurring coincidentally with and complicating the diagnosis of other rheumatic diseases. A suggested terminology characterizing more clearly the interrelationships of anatomic, synovial fluid, and clinical findings will be commented on.

Report of Cases 

Case 1.  —A