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June 1965

Principles of Biochemistry.

Arch Intern Med. 1965;115(6):754-755. doi:10.1001/archinte.1960.03860180126040

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That modern biochemistry is of fundamental importance in medical practice is well enough known. In fact, modern biochemistry is the system or language in terms of which most biological events are more informatively expressed. For example, a comprehensive understanding of modern pharmacology encompasses biochemical events: on what substrate a drug acts; why is it assumed or presently known to act that way; what inhibits, accentuates, or otherwise modifies its action, and so on and so forth. Most bio-chemical happenings are subject to a feedback system, whereby the product of interaction itself modifies the subsequent reaction of the substances which built it. These are simple enough and easily understandable phenomena. And they hold the key to an appreciation about what goes on in the body.

While this book refers to biochemical functions in the mammal generally, it makes specific reference to human biochemistry. As such, it has a clinical or

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