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December 1965

Progression of Reiter's Syndrome to Psoriatic Arthritis

Author Affiliations


From the Department of Medicine, Minneapolis Veterans Administration Hospital, and the University of Minnesota Medical School, Minneapolis.

Arch Intern Med. 1965;116(6):911-917. doi:10.1001/archinte.1965.03870060109023

During URING THE past 15 years Reiter's syndrome has been found in 70 patients at the Minneapolis Veterans Administration Hospital. Long-term study of these patients has brought to light several new aspects of the disease. Among these 70 patients, the chronic recurrent form of the disease often became indistinguishable from rheumatoid arthritis or ankylosing spondylitis. In seven patients whose case histories form the basis of this paper, the skin and joint lesions were exceptionally severe and eventually progressed until the disease very closely resembled psoriatic arthritis. One of these patients also exhibited the unusual complication of acute glomerulonephritis.

Report of Cases  The clinical, x-ray and biopsy findings in the following case histories will serve to support and illustrate these observations.

Case 1.  —A 42-year-old man experienced a sore tongue, urethritis, and penile lesions in November 1962, and two months later he had mild diarrhea. Examination revealed a geographic tongue, palatine