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August 1966

Meningitis Due to Sporotrichum schenckii

Arch Intern Med. 1966;118(2):145-149. doi:10.1001/archinte.1966.00290140049010

INVOLVEMENT of the central nervous system during the course of dissemination of fungus diseases is expected in cryptococcosis, anticipated in coccidioidomycosis and mucormycosis, well-recognized in nocardiosis and actinomycosis, known to occur occasionally in histoplasmosis, blastomycosis, aspergillosis, and chromomycosis, but to be distinctly rare in other systemic mycoses.

There are available to us only three acceptably documented cases,1-3 of central nervous system involvement by Sporotrichum schenckii. All three patients died from the infection. We are reporting another well-documented case. The patient has, to date, responded to treatment with amphotericin B in a manner suggesting probable recovery.

Report of a Case  A 58-year-old white male rice farmer became ill in October 1963, with complaints of lethargy, weakness, staggering gait, and a decrease in the sense of taste, smell, and hearing. Vomiting became frequent. Five months after onset, a lumbar puncture was done and revealed an increase in protein content and lymphocytes.