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October 1966

Hypercalcemia in Concurrent Hyperthyroidism and Hyperparathyroidism

Author Affiliations


From the Department of Medicine, Duke University Medical Center, Durham, NC. Dr. Breuer is presently with the Department of Medicine, University of Chicago, Chicago.

Arch Intern Med. 1966;118(4):310-313. doi:10.1001/archinte.1966.00290160010003

An occasional patient with hyperthyroidism demonstrates hypercalcemia. This association is uncommon enough, however, to warrant a careful search for other causes of serum calcium elevation. The patient described, who presented with severe hypercalcemia, proved to have both hyperthyroidism and primary hyperparathyroidism. His blood calcium levels returned to normal only after control of both illnesses.

Report of a Case  A 42-year-old Negro male teacher was admitted for the first time to Duke Hospital on Dec 17, 1964, with the chief complaint of extreme weakness. For the past two or three years he had had increased thirst, excessive urination, occasional nocturia, occasional postprandial vomiting, upper abdominal discomfort not typical of ulcer pain, and mild constipation. Four months before admission he noted malaise, easy fatigability, increased nervousness, excessive sweating, and heat intolerance. He lost 36 lb; although his appetite had remained good until the month before admission. During the three weeks prior to