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January 1967

Metastatic Brain Abscesses: A Retrospective Appraisal of 29 Patients

Author Affiliations


From the departments of medicine, Minneapolis Veterans Hospital and University of Minnesota Medical School, Minneapolis.

Arch Intern Med. 1967;119(1):25-31. doi:10.1001/archinte.1967.00290190073004

IN SPITE of the advent of antibiotics, the incidence of brain abscess has not changed over the past three decades.1-3 Its mortality and morbidity remain formidable. In previously reported series, its mortality ranged from 35% to 60% with a morbidity of 50% to 80% among the survivors.1-7 These depressing figures are due in part to the difficulty in establishing an early diagnosis. The present study was undertaken with the hope of gaining information which might be helpful in arriving at an earlier diagnosis.

Clinical Material  The case records of all patients with the diagnosis of brain abscess seen in the Minneapolis Veterans Administration Hospital over the ten-year period from 1955 to 1965 were reviewed. Twenty-one cases in which the abscess was the direct result of trauma were excluded. The diagnosis in the remaining 29 cases was established at surgery or autopsy. These cases were selected for study.The