THE FAMILY Cryptococcacae includes species of Cryptococcus and Candida. Clinical infections in man caused by members of this family are generally due to Candida albicans or less commonly Cryptococcus neoformans. In recent years, it has become clear that Candida tropicalis may also produce severe systemic infection in both man and experimental animals.1-5 Other members of the family include Candida parapsilosis, C pseudotropicalis, C krusei, C guilliermondii, C stellatoidea, Torulopsis glabrata, and the genus Rhodotorula. Disseminated infections due to these organisms are rarely reported in man. The single exception to this is subacute Candida endocarditis; approximately one third of these cases have been caused by species other than C albicans, usually C parapsilosis or C guilliermondii.6,7 Almost uniformly the subacute endocardial infections due to Candida species are limited to the heart valves and do not invade other tissues. Consequently, they constitute a special group and have been separated from
Louria DB, Blevins A, Armstrong D, Burdick R, Lieberman P. Fungemia Caused by "Nonpathogenic" Yeasts. Arch Intern Med. 1967;119(3):247–252. doi:10.1001/archinte.1967.00290210079004
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