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August 1967

Idiopathic Pulmonary Hemosiderosis: Severe Anemia Without Hemoptysis— One Year Follow-Up of Pulmonary Function

Arch Intern Med. 1967;120(2):220-223. doi:10.1001/archinte.1967.00300020092012

HEMOPTYSIS and anemia are common presenting symptoms of idiopathic pulmonary hemosiderosis (IPH).1,2 However, unexplained iron deficiency is an unusual presentation. A 22-year-old white man was seen in hematologic consultation with unexplained iron deficiency anemia. He had a normal chest x-ray film and no history of hemoptysis. Microscopic hematuria suggested IPH or Goodpasture's syndrome (GPS), and sputum examination for hemosiderin-laden macrophages was positive.

Hematologic and renal aspects of IPH have been reviewed recently,1,2 but little information is available concerning the long-term effects of pulmonary bleeding on pulmonary function. Initial and one year follow-up studies of pulmonary function were done.

Report of a Case  A 22-year-old printer was first admitted with a three-week history of fatigue. Two weeks earlier his family had noted he was pale. He was admitted to another hospital where the following data were obtained: hemoglobin level 7.6 gm/100 cc, red blood cell count (RBC) 3.45