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August 1967

Idiopathic Pulmonary Hemosiderosis: Severe Anemia Without Hemoptysis— One Year Follow-Up of Pulmonary Function

Author Affiliations

Rochester, NY

From the Department of Medicine, Hematology and Cardiopulmonary units of Strong Memorial Hospital of the University of Rochester (NY) School of Medicine and Dentistry. Drs. Aledort and Lord were fellows of the US Public Health Service. Dr. Aledort is now at Mount Sinai School of Medicine, New York; Dr. Lord is at the Maine Medical Center, Portland.

Arch Intern Med. 1967;120(2):220-223. doi:10.1001/archinte.1967.00300020092012

HEMOPTYSIS and anemia are common presenting symptoms of idiopathic pulmonary hemosiderosis (IPH).1,2 However, unexplained iron deficiency is an unusual presentation. A 22-year-old white man was seen in hematologic consultation with unexplained iron deficiency anemia. He had a normal chest x-ray film and no history of hemoptysis. Microscopic hematuria suggested IPH or Goodpasture's syndrome (GPS), and sputum examination for hemosiderin-laden macrophages was positive.

Hematologic and renal aspects of IPH have been reviewed recently,1,2 but little information is available concerning the long-term effects of pulmonary bleeding on pulmonary function. Initial and one year follow-up studies of pulmonary function were done.

Report of a Case  A 22-year-old printer was first admitted with a three-week history of fatigue. Two weeks earlier his family had noted he was pale. He was admitted to another hospital where the following data were obtained: hemoglobin level 7.6 gm/100 cc, red blood cell count (RBC) 3.45

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