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September 1967

Hyperparathyroidism in a Patient With Parathyroid Carcinoma: 15-Year Follow-Up

Arch Intern Med. 1967;120(3):349-352. doi:10.1001/archinte.1967.00300030091018

THE RARITY of hyperparathyroidism in patients with parathyroid carcinoma and the unusually prolonged course of the disease in a patient originally reported as a case of benign parathyroid adenoma 1 prompted this report.

Report of a Case  A 58-year-old male Negro porter had a giant cell tumor of the jaw removed in 1951. In 1958, he was admitted to the Bronx Municipal Hospital because of severe anorexia, 9.1-kg (20-1b) weight loss, and an increasingly large neck mass. Persistent hypercalcemia (to 16.7 mg/100 cc), low serum inorganic phosphorus (2.4 mg/100 cc), and increased alkaline phosphatase (8.1 Bodansky units) were noted. An en-bloc removal of a parathyroid tumor adherent to the right strap muscles and the right lobe of the thyroid was done. The pathologic diagnosis was parathyroid carcinoma, and the case was reported a second time.2In 1965, the patient entered the Hospital for Joint Diseases with the chief complaint