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June 1968

The Significance of Hyperventilative and Orthostatic T-Wave Changes on the Electrocardiogram

Arch Intern Med. 1968;121(6):518-523. doi:10.1001/archinte.1968.03640060032006

A group of 305 patients were studied to evaluate the significance of orthostatic and hyperventilative T-wave changes, orthostatic blood pressure changes, and the relationship of ischemic heart disease, as determined by treadmill stress testing, to these observed changes. The results indicate that orthostatic and hyperventilative T-wave changes are not at all an unusual finding in the younger age group and are not related to ischemic heart disease. In patients having ischemic heart disease, a stationary or decreased systolic blood pressure when changing from a sitting to a standing position was seen in the majority studied. The presence of orthostatic and hyperventilative T-wave changes did not confuse the interpretation of the treadmill stress test electrocardiogram when evaluated by our criteria for ischemic abnormality.