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October 1968

Small Cell Carcinoma of LungObservations on Four Patients Including One with a Myasthenic Syndrome

Author Affiliations

Rochester, Minn

From the sections of medicine (Dr. Divertie), experimental and anatomic pathology (Dr. Brown), and physiology (Dr. Lambert), Mayo Clinic and Mayo Foundation, and the Mayo Graduate School of Medicine (University of Minnesota), Rochester, Minn (Dr. Greene).

Arch Intern Med. 1968;122(4):333-339. doi:10.1001/archinte.1968.00300090043010

The fine structure of four small cell carcinomas of the lung is described. Cells from the tumor of one patient, who has a myasthenic syndrome, contained a well-developed, roughsurfaced endoplasmic reticulum and an enlarged Golgi apparatus. These were much less apparent in the three tumors unassociated with the myasthenic syndrome.