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Article
April 1969

Major Endocrine Surgery for the Treatment of Cancer of the Breast in Advanced Stages.

Author Affiliations

Chicago

 

Edited by M. Dargent, MD, and C. Romieu, MD. Price not given. Pp 315, with 99 figures, 162 tables, 4 plates, 3 graphs. Simep Editions, 14 Ave Rockefeller, 69, Lyon, France, 1967.

Arch Intern Med. 1969;123(4):476. doi:10.1001/archinte.1969.00300140122037

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Abstract

One hundred seventeen experts have contributed to a review of the present status of endocrine surgery in the management of advanced cancer of the breast. The present volume is the result of a meeting held in Lyon, France, May 5 to 7, 1966. Introduced by Huggins and opened with a paper by Dao, the symposium volume brings together the results obtained in a number of medical centers with adrenalectomies, adrenal-splenic transplantation, and surgical and radioactive hypophysectomies. In addition, sections are devoted to fundamental biological studies and a comparison of medical and surgical techniques for the control of breast cancer.

In over 2,600 bilateral adrenalectomies, objective responses were obtained in 15% to 38% of cases, with an operative mortality of 2.7% to 4%. In more than 1,500 hypophysectomies, objective improvement occurred in 19% to 38% of cases, with an operative mortality of up to 6%. The variability of response emphasizes the

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