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May 1969

Symposium on Renal Transplantation

Author Affiliations

Durham, NC

From the Department of Medicine, Duke University Medical Center, Durham, NC.

Arch Intern Med. 1969;123(5):483-484. doi:10.1001/archinte.1969.00300150001001

Introduction  The past decade has witnessed striking advances toward the successful achievement of organ transplantation, particularly in the area of renal transplantation. Of the many important factors that have contributed to such rapid progress, at least three can be identified whose contribution to the increasing success and application of renal transplantation would seem to have been particularly influential: (1) The nature, composition, or location of the renal transplantation antigens themselves may be such that they are happily and inherently less inductive of an immune response than those of certain other organ systems, ie, skin. In consequence, the immunological rejection of alien renal tissue by the host may have been fortuitously somewhat easier to control with available methods of immunosuppression. (2) The fortunate presence of paired healthy kidneys, one of which is not essential for life, has permitted the considered use of optimally viable organs from living volunteer donors. (3) The

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