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Article
June 1969

Virology Monographs, vol 2.

Arch Intern Med. 1969;123(6):731. doi:10.1001/archinte.1969.00300160121024

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Abstract

The juxtaposition of "The Simian Viruses" (R. N. Hull, 66 pages) and "Rhinoviruses" (D. A. J. Tyrell, 116 pages) in the same volume appears to have been fortuitous—there is no link beyond the common concern with viruses. Yet, there are many similarities between viruses of simian and human origin, as is apparent from Hull's discussion of viruses isolated from nonhuman primates and the classification of 57 agents that is proposed.

In a final chapter, "General Discussion and Considerations," the aspects of simian viruses that are of medical importance are reviewed. The major importance of these agents to medicine lies in their potential for confusing virological diagnosis. Typically, simian viruses are indigeneous and become apparent only as cells derived from nonhuman primates are used in tissue culture.

Oncogenicity was demonstrated in suckling hamsters with the simian adenovirus 40 (SV 40). Although many humans were inadvertantly inoculated with live SV 40 virus

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