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March 1970

Hereditary Nephritis in the NegroReport of a Kindred

Arch Intern Med. 1970;125(3):451-458. doi:10.1001/archinte.1970.00310030061004

A Negro kindred which demonstrated an unusual racial incidence of hereditary nephritis, also exhibited a number of other relatively uncommon features. Three members of the kindred had cataracts; all three had nephritis, one died of renal failure, and two had deafness. Two members, 15 and 16 years old, had large urinary excretion of protein satisfying the criteria of the nephrotic syndrome, and both had eighth nerve involvement. A 17-year-old girl died of renal failure, and a 4-month-old boy has an abnormal urine sediment.