[Skip to Navigation]
May 1970

Interferon: Virology Monographs,

Arch Intern Med. 1970;125(5):899-900. doi:10.1001/archinte.1970.00310050137031

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This review is written primarily from the viewpoint of a clinician with a subspecialty interest in infectious diseases. Since its discovery in the 1950's by Isaacs and Lindenmann, interferon has become increasingly recognized as a probable significant defense mechanism in viral infections. Its importance may also extend to other nonviral, predominantly intracellular infections (malaria, toxoplasmosis, brucellosis, etc). Research contributions have multiplied to the extent that it is difficult to find a current journal related to virology, microbiology, or infectious diseases that does not at least mention this substance. The book, Interferon: Virology Monographs, is an extensively referenced, up-to-date review of the subject by a single author, Jan Vilcěk. Topics such as assay methods, synthesis, action, role in human infections, and its potentiality as a therapeutic agent are covered.

I found the book well organized, balanced, and lucid. Concepts are introduced and explained before their subsequent use in the book.

First Page Preview View Large
First page PDF preview
First page PDF preview
Add or change institution