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Clinical studies of the early treatable stages of neoplastic disease have been extensive, and the natural history of more advanced metastatic cancer has been fairly well described. There have been comparatively few studies of intermediate stages: the early stages of metastatic disease. This book focuses on that problem, particularly with respect to solitary metastases; thus it fills an important need.
The historical background of this complex area is well presented, and references are complete. It is a valuable source book. Areas relating to diagnostic radiology, (including radioisotope diagnosis) and radiotherapy are critically and effectively reviewed and well presented. The same is generally true of surgery. The quality of sections relating to medicine and chemotherapy is variable. There is some tendency to repetitiousness in the presentation and discussion of solitary metastases in various organs. Also, a substantial portion of the book deals with areas of marginal relevance to the solitary metastasis
Frei E. Solitary Metastases.. Arch Intern Med. 1970;125(6):1081–1082. doi:10.1001/archinte.1970.00310060159027
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