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September 1970

Experimental Studies of Inhaled Materials: A Basis for Respiratory Models

Author Affiliations

Rochester, NY

From the Department of Radiation Biology and Biophysics, University of Rochester, Rochester, NY.

Arch Intern Med. 1970;126(3):466-470. doi:10.1001/archinte.1970.00310090096010

Recent technological advancements and newly available radioactive, isotopic aerosols have accelerated and broadened experimental investigations of dust deposition and retention in the human respiratory system. Collectively, these studies have provided a much improved basis for designing respiratory models of interest and value to biomedical research, and particularly to environmental scientists, occupational hygienists, and health physicists. This communication reviews these models chronologically and includes some recent information which appears to correlate deposition and clearance to measurements of the inhaled aerosol. It concludes with a brief critique.

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