The disturbances associated with mineral metabolism in uremia are examined in terms of alterations which may affect the adenyl cyclase system, calcium-activated ATPase, and divalent cation binding. The participation of these mechanisms in physiological regulatory processes and their potential for alteration in uremia are discussed.
Gitelman HJ. Uremic Toxins and Mineral Metabolism: Potential Sites of Interaction. Arch Intern Med. 1970;126(5):793–800. doi:10.1001/archinte.1970.00310110063008
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