A wide variety of acute and chronic psychiatric symptoms have been seen in patients taking lysergic acid diethylamide (LSD).1 We report a case of particular interest because the patient developed focal neurologic signs.
A 14-year-old boy with no previous history of epilepsy, cardiovascular or neurological disease, or head trauma was hospitalized because of a short generalized seizure characterized by eye rolling, clonic and tonic movements, and loss of consciousness. For one month prior to admission, his mother had noted episodes of elation and drowsiness. Family history was unremarkable. A history obtained from four of his companions revealed that the patient had taken four LSD capsules shortly before the seizure. No other capsules were found.Physical examination revealed a well-developed boy, mildly lethargic and restless. The blood pressure was 102/70 mm Hg; pulse rate, 88 beats per minute and regular; respiratory rate, 16 per minute; and temperature 100.6