[Skip to Navigation]
April 1971

Myocardial Blood Flow: Measurement by a Coincidence Counting System and Single Bolus of 84Rb

Author Affiliations


From the Department of Medicine, Indiana University School of Medicine and the Krannert Institute of Cardiology, Marion County General Hospital, Indianapolis.

Arch Intern Med. 1971;127(4):767-772. doi:10.1001/archinte.1971.00310160245022

Animal experiments demonstrated that myocardial blood flow (MBF) as measured by the coincidence system and a concomitant Fick determination were very similar, varying from +9.9% to -7.9% with a mean absolute error of 5.3%. Human studies have demonstrated that (1) the average MBF in normal subjects is 269±61 ml/min/total heart, which represents 5.2±1.6% of the simultaneous cardiac output, (2) MBF determined by the coincidence technique is a reproducible measurement and has appropriate directional change with stresses imposed to augment myocardial oxygen demand, and (3) patients with significant coronary artery disease have a decreased flow reserve.

Add or change institution