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December 1971

The Incidence Study— Study Design and Methods

Author Affiliations

Chapel Hill, NC; Claxton, Ga

From the Department of Epidemiology, University of North Carolina, Chapel Hill (Drs. Cornoni, Cassel, and Tyroler, and Lynn Waller). Dr. Hames is in private practice in Evans County, Georgia.

Arch Intern Med. 1971;128(6):896-900. doi:10.1001/archinte.1971.00310240050005

A biracial sample of 3,102 persons from Evans County, Georgia, was first examined in 1960-1962. Of this original cohort 2,530 persons were reexamined in 1967-1969. From these two observations the incidence rates for the 87-month period of both coronary heart disease and stroke were determined. The recent examination procedure included a complete medical history and physical examination, with a detailed questionnaire for evidence of cerebrovascular disease and symptoms of transient cerebral ischemia, an electrocardiogram, chest x-ray film, laboratory procedures, and sociological and physical activity questionnaires.

Between 1960 and 1962 a study of the prevalence of coronary heart disease was conducted in Evans County, Georgia.1 For this purpose 100% of the population aged 40 years and older and a 50% random sample of those 15 to 39 years were invited to undergo a complete medical examination. Cooperation was obtained from 3,102 individuals, representing 92% of those eligible for examination.


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