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Article
February 1972

MorCarcinogenesis,rimental Respiratory Carcinogenesis,

Author Affiliations

Harlingen, Tex

Arch Intern Med. 1972;129(2):367. doi:10.1001/archinte.1972.00320020211021

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Abstract

This is No. 21 in the Atomic Energy Commission (AEC) Symposium Series; it supplements No. 18, Inhalation Carcinogenesis, in the series. This useful paperback is a record of the proceedings of the conference on the Morphology of Experimental Respiratory Carcinogenesis held by the Biology Division, Oak Ridge National Laboratory, in May 1970 and sponsored by the National Cancer Institute and the AEC.

This conference considered specifically the induction of tumors, using various methods of exposure and different carcinogens and cocarcinogens in the respiratory tracts of several laboratory and domestic animals. Also presented were fundamental pulmonary structure and function, human lung tumors, animal models for pulmonary carcinogenesis (including the most recent advances in that field), and proposals for a unified lung tumor classification in animals.

Primary bronchogenic carcinoma forms the largest single component of the worldwide increase in mortality from cancer. Since practically all primary cancers of the lung arise from

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