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March 1972

Atherosclerosis: Proceedings of the Second International Symposium.

Arch Intern Med. 1972;129(3):506-507. doi:10.1001/archinte.1972.00320030126025

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This is a carefully edited and well printed account of the 1969 symposium in Chicago at which most aspects of the pathogenesis and ways of controlling atherosclerosis were presented and discussed by experts from Asia, Europe, and America. All theories of pathogenesis except the intimal hemorrhage hypothesis of Winternitz were argued persuasively. Local synthesis, mural thrombosis, and infiltration of plasma cholesterol esters figure as predominant or exclusive causes. The program of the symposium provided an orderly and logical development of the topics. Atherosclerosis is a complete account of the state of this problem prior to 1970.

Schettler's keynote address shows (Fig 1) that the plasma cholesterol of normal Germans fell nearly 40% between 1942 and 1947; Fig 2 shows there was a parallel fall in the deaths from pulmonary embolism; a similar fall in deaths from coronary heart disease also occurred in Germany and in Norway. Figures 3 to 5

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