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August 1972

Small Bowel Perforation in Regional Enteritis Resulting From Adenocarcinoma

Author Affiliations


From the Section of Gastroenterology and Surgery, New England Medical Center and Tufts University Medical School, Boston. Dr. Levitan is now with the Veterans Administration West Side Hospital, Abraham Lincoln School of Medicine, University of Illinois Medical Center, Chicago.

Arch Intern Med. 1972;130(2):275-276. doi:10.1001/archinte.1972.03650020095017

Since the first report in 1956 by Ginsburg and associates1 of adenocarcinoma of the small intestine occurring in patients with regional enteritis, a total of 21 similar cases have been reported.2-5 None of these patients perforated their bowel.

Free small bowel perforation in the course of regional enteritis, in general, is a rare event.4,6 In none of these patients did the small bowel perforation result from a tumor.

Since evidence regarding the association of regional enteritis and carcinoma seems to be emerging1-5 and small bowel perforation in the course of regional enteritis4,6-10 is a rare complication, we wish to report a patient in whom adenocarcinoma of the small bowel resulted in a free small bowel perforation after 24 years of regional enteritis.

Patient Summary  A 43-year-old white woman was admitted for the first time on July 20,1968, to the New England Medical Center Hospitals (195-961).

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