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September 1972

Disseminated Intravascular Coagulation in Miliary Tuberculosis

Author Affiliations


From the Blood Research Laboratory, New England Medical Center Hospitals and the Department of Medicine, Tufts University School of Medicine, Boston. Dr. Mavligit is now with the M. D. Anderson Hospital, Houston, and Dr. Binder is now with the Georgetown University Hospital, Washington, DC.

Arch Intern Med. 1972;130(3):388-389. doi:10.1001/archinte.1972.03650030066015

Disseminated intravascular coagulation (DIC), now a well recognized entity, has been reported in association with a number of bacterial, viral, fungal, rickettsial, and protozoal infections, as well as in noninfectious processes.1,2 To our knowledge, DIC has been reported only once in association with fatal miliary tuberculosis.3 We wish to present the second case, this time in a patient who survives.

Patient Summary  The patient, (NEMCH No. 80-88-56), a 68-year-old Chinese man, was seen in the emergency room on April 12,1971, for head trauma after a fall. A shaking chill and temperature of 39.4 C (103 F) prompted an admission.On previous admissions the diagnosis of rheumatic heart disease with aortic and mitral valve involvement and chronic atrial fibrillation was made. In March 1971, he also had a documented myocardial infarction. X-ray film of the chest at that time showed clear lung fields.Physical examination showed a wasted, elderly

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