[Skip to Navigation]
September 1972

Cerebral Embolism: Review and Current Perspectives

Author Affiliations

Iowa City

From the Department of Neurology and Neurosensory Center, College of Medicine, University of Iowa, Iowa City. Dr. Calkins is now with the Department of Medicine, Michigan State University, College of Human Medicine, and is also in private practice in Lansing, Mich.

Arch Intern Med. 1972;130(3):430-436. doi:10.1001/archinte.1972.03650030102023

In a discussion of old and new concepts of cerebral embolism, two cases are used to illustrate the phathophysiology of atheroembolism in producing intermittent and lasting neurologic deficits. Emboli are due to both cardiogenic and noncardiogenic sources. The onset is characteristically abrupt, but premonitory warnings may occur. The risk of recurrent embolism must be weighed against the risk of anticoagulant therapy, which may cause lethal hemorrhage into the infarcted area. Definitive therapy may require surgical intervention. It seems likely that embolism occurs more frequently than has been previously stated, and these patients should be identified to permit appropriate medical and surgical therapy.