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The author has written this book "for specialists in clinical immunology and allergy—for practitioners, teachers, investigators, and postgraduate trainees in the various branches of internal medicine, pediatrics and surgery." The book attempts to describe almost every manifestation of human pathology ever conceived as being on an immunological basis. The result is a series of very incomplete comments on most of the conditions mentioned. In fact, the author's goal of providing a comprehensive text to satisfy the range of readership he aims for is an impossibility. The major phases of clinical immunology are covered completely and expertly; the hundreds of minor questionable syndromes could have been lumped and mentioned briefly as such. The investigator who expects to find working details in laboratory technic, such as radioimmunoassay or immunoelectrophoresis, is bound to be disappointed. A complete up-to-date chapter on the former could have constituted a most valuable asset for the research